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Prolactin

Also known as: PRL, lactotropin

A pituitary hormone best known for milk production, whose excess can disrupt fertility and libido in both sexes.

What is Prolactin?

Prolactin is a hormone made by the pituitary gland that stimulates breast milk production after childbirth. Outside of pregnancy and breastfeeding, high prolactin can suppress the reproductive hormones LH and FSH, causing infertility, low libido, and menstrual changes in women and low testosterone in men.

Why it matters

Elevated prolactin is a common, treatable cause of infertility, irregular periods, and low testosterone. It is a routine part of evaluating these problems and can reveal a benign pituitary tumor (prolactinoma).

What it measures

Serum prolactin concentration. Levels rise with stress, sleep, meals, and nipple stimulation, so testing conditions matter.

Reference & optimal ranges

Reference ranges vary by lab, assay, age, and sex. The ranges below reflect commonly published adult intervals and are for education only always interpret results with the range printed on your own lab report and a clinician.

Menng/mL
Standard range
Women (non-pregnant)ng/mL
Standard range
High Prolactin

High prolactin (hyperprolactinemia) can suppress reproductive hormones and often warrants imaging to rule out a pituitary tumor.

Common symptoms

  • Irregular or absent periods
  • Milky nipple discharge (galactorrhea)
  • Low libido, erectile dysfunction
  • Infertility

Potential causes

  • Prolactinoma (pituitary tumor)
  • Medications (antipsychotics, some antidepressants)
  • Hypothyroidism
  • Stress, recent meal, or nipple stimulation
  • Pregnancy/breastfeeding
Low Prolactin

Low prolactin is uncommon and rarely clinically significant, occasionally seen with pituitary underactivity.

Common symptoms

  • Usually none

Potential causes

  • Hypopituitarism
  • Certain medications (dopamine agonists)

How to improve your Prolactin

Lifestyle

  • Note testing conditions

    Avoid nipple stimulation and heavy stress before testing; a fasting morning draw is preferred.

Nutrition

  • General balanced diet

    No specific diet lowers prolactin; treat the underlying cause.

Exercise

  • Regular activity

    Supports overall pituitary and reproductive health.

Sleep

  • Consistent sleep

    Prolactin rises during sleep; test after being awake a few hours.

Frequently asked questions

Scientific references

Pending clinician reviewPublished Jul 2, 2026 · Updated Jul 2, 2026

Educational information, not medical advice. This page is for general education and does not replace diagnosis or treatment by a licensed clinician. Do not start, stop, or change any medication, supplement, or treatment based on this content. Reference and optimal ranges vary between laboratories interpret your results with the range on your own report and a qualified professional.

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