What is CRP?
C-reactive protein (CRP) is made by the liver and rises with inflammation anywhere in the body. The high-sensitivity assay (hs-CRP) detects the low-grade, chronic inflammation linked to cardiovascular disease. Standard CRP is used for acute infection and inflammatory conditions; hs-CRP is used for cardiovascular risk stratification.
Why it matters
Chronic low-grade inflammation contributes to atherosclerosis, insulin resistance, and aging. hs-CRP adds independent information to cholesterol for predicting heart attack and stroke risk.
What it measures
The blood concentration of C-reactive protein. hs-CRP measures the low range relevant to cardiovascular risk.
Reference & optimal ranges
Reference ranges vary by lab, assay, age, and sex. The ranges below reflect commonly published adult intervals and are for education only always interpret results with the range printed on your own lab report and a clinician.
High CRP indicates inflammation. Very high levels usually mean infection or an inflammatory condition; mildly elevated hs-CRP suggests higher cardiovascular risk.
Common symptoms
- Depends on cause; may accompany infection or inflammatory disease symptoms
Potential causes
- Infection
- Autoimmune/inflammatory disease
- Obesity and insulin resistance
- Smoking
- Recent injury or surgery
- Cardiovascular disease risk (low-grade elevation)
Low CRP is favorable, indicating little systemic inflammation.
Common symptoms
- None
Potential causes
- Healthy, low-inflammation state
How to improve your CRP
Lifestyle
Quit smoking, lose excess fat
Both are major drivers of chronic inflammation and elevated hs-CRP.
Nutrition
Anti-inflammatory diet
Emphasize vegetables, fruit, fiber, omega-3 fats; limit ultra-processed foods and added sugar.
Exercise
Regular activity
Consistent moderate exercise lowers chronic inflammation.
Sleep
Prioritize sleep
Poor sleep raises inflammatory markers including CRP.
Frequently asked questions
Scientific references
- C-Reactive Protein (CRP) Test MedlinePlus, U.S. National Library of Medicine
- hs-CRP Test Testing.com
Educational information, not medical advice. This page is for general education and does not replace diagnosis or treatment by a licensed clinician. Do not start, stop, or change any medication, supplement, or treatment based on this content. Reference and optimal ranges vary between laboratories interpret your results with the range on your own report and a qualified professional.